211 System status, or system help reply 214 Help message [Information on how to use the receiver or the meaning of a particular non-standard command; this reply is useful only to the human user] 220 <domain> Service ready 221 <domain> Service closing transmission channel 250 Requested mail action okay, completed 251 User not local; will forward to <forward-path> 354 Start mail input; end with <CRLF>.<CRLF> 421 <domain> Service not available, closing transmission channel [This may be a reply to any command if the service knows it must shut down] 450 Requested mail action not taken: mailbox unavailable [E.g., mailbox busy] 451 Requested action aborted: local error in processing 452 Requested action not taken: insufficient system storage 500 Syntax error, command unrecognized [This may include errors such as command line too long] 501 Syntax error in parameters or arguments 502 Command not implemented 503 Bad sequence of commands 504 Command parameter not implemented 550 Requested action not taken: mailbox unavailable [E.g., mailbox not found, no access] 551 User not local; please try <forward-path> 552 Requested mail action aborted: exceeded storage allocation 553 Requested action not taken: mailbox name not allowed [E.g., mailbox syntax incorrect] 554 Transaction failed